CD11b Antikörper

Produktnummer ABIN182004

Dieser Anti-CD11b Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD11b in FACS, IP und IHC (fro). Geeignet für Ratte.

Kurzübersicht für CD11b Antikörper (ABIN182004)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: OX-42

Produktdetails anti-CD11b Antikörper

Aufreinigung: Affinity chromatography on Protein G

Endotoxin-Niveau: Low Endotoxin

Immunogen: Rat peritoneal macrophages. Spleen cells from immunised BALB/c mice were fused with cells of the NSO/U mouse myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation. Immunohistochemistry on frozen sections: 1/50 - 1/100, Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate- lysine-paraformaldehyde). Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.2

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: CD11b

Hintergrund: The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35 % of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain.Synonyms: CD11 antigen-like family member B, CR-3 alpha chain, CR3A, Cell surface glycoprotein MAC-1 subunit alpha, ITGAM, Integrin alpha-M, Leukocyte adhesion receptor MO1, MAC1, Neutrophil adherence receptor

Gen-ID: 10116

UniProt: Q63001

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation